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Estimated Glomerular Filtration Rate (eGFR) CKD-EPI

Published: July 27, 2026Updated: August 25, 2026

The eGFR CKD-EPI biomarker measures kidney function by estimating the rate at which the kidneys filter waste from the blood. It is calculated using a formula that includes serum creatinine, age, sex, and race.

Quick summary

eGFR CKD-EPI estimates kidney filtration rate to assess kidney function.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

Units
mL/min/1.73m²
Clinical utility
diagnostic
Result kind
quantitative
FDA-cleared
CKD-EPI eGFR Calculator, MDRD eGFR Calculator
interpretation: {"text":"60–120 mL/min/1.73m²: Indicates normal kidney function.","label":"Normal"}; {"text":"<60 mL/min/1.73m²: Suggests kidney dysfunction or chronic kidney disease.","label":"Abnormal"}

The eGFR CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) is a widely used biomarker for assessing kidney function. It provides a more accurate estimation of glomerular filtration rate (GFR) compared to older equations, especially in patients with higher GFR levels.

This biomarker is crucial for diagnosing and managing chronic kidney disease (CKD). It helps in identifying patients at risk of CKD progression and in monitoring the effectiveness of treatments.

The eGFR CKD-EPI is calculated using serum creatinine levels, age, sex, and race. A value between 60 and 120 mL/min/1.73m² is generally considered normal, indicating healthy kidney function.

Frequently asked questions

What is a normal eGFR CKD-EPI value?
A normal eGFR CKD-EPI value is typically between 60 and 120 mL/min/1.73m².
How is eGFR CKD-EPI calculated?
eGFR CKD-EPI is calculated using a formula that includes serum creatinine, age, sex, and race.
  1. 1
    National Kidney Foundation: eGFRSource
  2. 2
    CKD-EPI Creatinine EquationSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy